Toxicological Profile of Aluminium Sulphate and Effect on Protein Profile in Albino Rat

Authors

  • Neelam Upadhyay Department of Zoology, School of Life Sciences, Khandari Campus, Dr. B.R. Ambedkar University, Agra-282002, U.P., India. http://orcid.org/0000-0001-8004-7543
  • P. K. Singh Department of Zoology, School of Life Sciences, Khandari Campus, Dr. B.R. Ambedkar University, Agra-282002, U.P., India.
  • Reena Yadav Department of Zoology, School of Life Sciences, Khandari Campus, Dr. B.R. Ambedkar University, Agra-282002, U.P., India. http://orcid.org/0000-0003-2208-4500

Keywords:

Toxicological Profile, Protein Profile, Aluminium Sulphate, Albino Rat

Abstract

World is full of xenobiotic substances such as heavy metal, pesticide and other pollutic agents. Heavy metal is a metallic element of relatively high density greater than 4gm/cm3 or 5 times more greater than water and is toxic even at low concentration. Heavy metals occur as a natural constituent of earth crust, can be emitted into environment by both natural and anthropogenic causes. Major cause of emission is the mining operations. Predetermined doses of aluminium sulphate in acute (1d) and subacute (7, 14, 21, 28ds) treatments revealed significant increase in albumin and globulin. The results are encouraging and highlight the toxic profile of aluminum sulphate and its effect on protein profile in albino rat.

Downloads

Download data is not yet available.

References

Bingham, E., Cohrssen, B. & Powell, C.H. (2001). Patty's Toxicology. Volumes 1–9, 5th ed., John Wiley & Sons. New York, N.Y. V2 399.

Connor, D.J., Jope, R.S. & Harrell, L.E. (1988). Chronic, oral aluminum administration to rats: Cognition and cholinergic parameters. Pharmacol. Biochem. Behav., 31(2): 467–474. https://doi.org/10.1016/0091-3057(88)90375-9.

Duruibe J.O., Ogwuegbu M.O.C. & Egwurugwu J.N. (2007). Heavy Metal Pollution and Human Biotoxic Effects. Int. J. Phys. Sci., 2(5): 112–118.

Finney, D.J. (1971). Probit analysis. 3rd ed., Cambridge University Press, Cambridge. pp. 333.

Arora, S., Saxena, P.N. & Sharma, H.N. (2017) Serum biochemical alterations in albino rats following decis intoxication. International Journal of Interdisciplinary Research, 4(6): 7-12.

Shaw, C.A., Seneff, S., Kette, S.D., Tomljenovic, L., Oller, J.W., Jr, & Davidson, R.M. (2014). Aluminum-induced entropy in biological systems: implications for neurological disease. J. Toxicol., Vol 2014, Article ID 491316. https://doi.org/10.1155/2014/491316.

Singh, N.D., Sharma, A.K., Dwivedi, P., Patil, R.D. & Basheer Ahamad. D. (2006). Toxicity of endosulfan and citrinin alone and in combination in pregnant rats: Clinico-Haematological and serum biochemical alterations. Indian J. Vet. Pathol., 30(1): 27-31.

Umminger, B.L. (1977). Relation of whole blood sugar concentrations in vertebrates to standard metabolic rate. Comp. Biochem. Physiol. A: Physiol., 56(4): 457-460.

Downloads

Abstract views: 24 / PDF downloads: 8

Published

2018-10-06

How to Cite

Upadhyay, N., Singh, P. K., & Yadav, R. (2018). Toxicological Profile of Aluminium Sulphate and Effect on Protein Profile in Albino Rat. Advances in BioScience, 9(4), 99–102. Retrieved from https://journals.sospublication.co.in/ab/article/view/253

Issue

Section

Articles