Evaluation, Antioxidant, Antimitotic and Anticancer Activity of Iron Nanoparticles Prepared by Using Water Extract of Vitis vinifera L. Leaves
Keywords:
Fe3O4, Nanoparticles, Allium cepa assay, Anti-inflammatory, AntioxidantAbstract
The water extract of Vitis vinifera was used for the rapid synthesis of the iron nanoparticle, which is very simple and eco-friendly in nature. The UV-visible spectroscopy technique was employed to establish the formation of which inhibition onion root growth in a dose-dependent manner. A decrease in the mitotic index may indicate its genotoxic effect on Allium cepa root assay. Nanoparticle was studied for its in vitro anti-inflammatory and antioxidant activity using different models, all the testing, gave significant correlation existed between concentrations of the nanoparticle and percentage inhibition of protein denaturation and scavenging free radicals. These results clearly indicate that iron nanoparticle is effective against inflammation and free radical-mediated disease.
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